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Pathogenes mission is to develop molecular tools for the diagnosis and treatment of animal diseases.

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Good Lesson from 2024
Nyambe Pathogenes made good strides in our horse drug development and case analysis this year. Each case gives us insight into the...
sellison23
Jan 3
302


S. neurona may elicit the JAK/STAT pathway in disease
Tongue paresis following S. neurona infection Do you wonder why researchers often can't find Sarcocystis neurona in the tissues of a...
sellison23
Sep 24, 2024
107


Equine protozoal myeloencephalitis in 2002
As we burn 20 year old files, as is our custom, we incinerated the early challenge experiment raw data. The signed exam forms, the CBC...
sellison23
Aug 16, 2024
201


The evidence S. neurona SAG1 is associated with polyneuritis
Pathogenes Inc associates infection with S. neurona strain SAG 1 with polyneuropathies. Two horse studies provide evidence. The killed...
sellison23
Jun 26, 2024
163


What about S. neurona
We had a lot of questions about Sarcocystis neurona and the complications that veterinarians and owners see in horses with Sarcocystis...
sellison23
Mar 7, 2024
124


Putative mechanism of CRP’s relationship to polyneuritis equi assay results
I spoke with Dr. Stefan Rose John, Institute of Biochemistry in Kiel Germany, a few years ago. Work he published in 2012 explains the...
sellison23
Oct 16, 2023
265


Field Effectiveness Study for PNE
Our polyneuritis (PNE) field study was a multi-site historical controlled, GCP (VICH GL9) study conducted under field conditions to...
sellison23
Oct 10, 2023
412


S. neurona SAG 6 gets attention
In 2000 Dr. Ellison investigated various genotypes of Sarcocystis neurona and Sarcocystis falcatula that were used by investigators T....
sellison23
Sep 4, 2023
130


Cell danger response: EPM or PNE?
The cell danger response (CDR) is a universal response to environmental threat or injury. Once the CDR is triggered, healing can’t be...
sellison23
Mar 22, 2023
366


Identification of biomarkers to slow neurodegenerative diseases
Biomarkers for treating neurodegenerative diseases
sellison23
Mar 15, 2023
156


Pathogenes Newsletter January 2023
The polyneuritis equi (PNE) field study has almost reached enrollment, but we need a few more horses. If you know anyone with a horse...
sellison23
Jan 2, 2023
192


EMD or EDM What's the difference?
EDM and EMD explained
sellison23
Dec 14, 2022
246


The difference between “EPM” testing formats
The difference between EPM testing formats is explained
sellison23
Jun 14, 2022
1,377


Predicting the severity of EPM is possible
Predicting the severity of EPM using early signs
sellison23
May 20, 2022
832


What is the difference between EPM, EMS, and PNE (polyneuritis)
A pictorial description of sarcocystis infections in horses
sellison23
May 13, 2022
692


Gathering Data on EPM and PNE (polyneuritis equi)
Here is a photograph of some of our research yearlings. This herd was vaccinated with recombinant SAG 1 vaccine and challenged with a...
sellison23
May 9, 2022
326


The MP2/MPP ELISA in the differential diagnosis of polyneuritis (PNE)
The first time I spoke with Linda Turcotte, in 2015, she told me the tale of her old horse, Bay State Nestle. I thought we could help,...
sellison23
Apr 30, 2022
1,047


Interpreting S. neurona antibody tests
Explain what antibody tests in EPM mean
sellison23
Apr 24, 2022
649


Can polyneuritis be diagnosed with NfL found in serum, plasma, or exosomes?
Neurofilament light may be measurable and stratify patients to level of disease
sellison23
Apr 18, 2022
291


Test twice, treat once The PNE (polyneuritis) plan
Neurofilament light is associated with polyneuritis equi, PNE
sellison23
Apr 13, 2022
332
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